WILLIAM J. MURPHY

Associate Professor
Department of Veterinary Integrative Biosciences

College of Veterinary Medicine & Biomedical Sciences
Texas A&M University
TAMU 4458
College Station, TX 77843-4458
Phone: 979.458.0906
Fax: 979.845.9972
E-mail: wmurphy@cvm.tamu.edu
Genetics Department Web page

Keywords: Mammalian comparative genomics, Feline genomics, Mammalian phylogeny and evolution, Felid evolution

Research Interests: Mammalian phylogenetics and molecular evolution, Feline evolutionary genomics, Y chromosome evolution, Genetics of hybrid sterility

Disciplines:
Comparative Genomics, Molecular Phylogenetics and Evolution.

Selected Publications
Davis, B. W., Raudsepp, T., Pearks Wilkerson, A. J., Agarwala, R., Schäffer, A. A., Houck, M., Chowdhary, B. P., and W. J. Murphy. 2009. A high-resolution cat radiation hybrid and integrated FISH mapping resource for phylogenomic studies across Felidae. Genomics. 93: 299-304.

Miller, W., Drautz, D. I., Janecka, J. E., Lesk, A.M., Ratan, A., Tomsho, L.P., Packard, M., Zhang, Y., McClellan, L., Qi, J., Zhao, F., Gilbert, M.T.P., Dalén, L., Arsuaga, J.L., Ericson, P.G.P., Huson, D. H., Helgen, K. M., Murphy, W.J., Götherström, A., and S.C. Schuster. 2009. The mitochondrial genome sequence of the Tasmanian tiger (Thylacinus cynocephalus). Genome Research 19: 213-220.

Janecka, J. E., Helgen, K. M., Lim, N., Baba, M., Izawa, M., Boeadi, and W. J. Murphy. 2008. Evidence for multiple species of Sunda colugo. Current Biology. 18: pR1001-1003.

Pearks-Wilkerson, A. J., Raudsepp, T., Graves, T., Warren, W., Chowdhary, B. P., Skow, L. C., and W. J. Murphy. 2008. Physical mapping, gene discovery, and comparative analysis of X-degenerate genes from the domestic cat Y chromosome. Genomics. 92: 329-338.

Jane�ka, J. E., Jackson, R., Li, D.-Q., Zhang, Y.-Q., F., Munkhtsog, B., Buckley-Beason, V., and W. J. Murphy. 2008. Population monitoring of snow leopards using noninvasive collection of scat samples: a pilot study. Animal Conservation. In press.

Jane�ka, J. E., Miller, W., Pringle, T. H., Wiens, F., Zitzmann, A., Helgen, K. M., Springer, M. S., and W. J. Murphy.  2007. Molecular and genomic data identify the closest living relative of primates. Science 318: 792-794.

Springer, M. S., Burk, A., Meredith, R., Eizirik, E., Teeling, E. C., O'Brien, S. J., and W. J. Murphy. 2007. The adequacy of morphology for reconstructing the early phylogenetic history of placental mammals. Systematic Biology 56: 673-684.

Murphy, W. J., Pringle, T., Crider, T., Springer, M. S., and W. Miller. Using genomic data to unravel the root of the placental mammal phylogeny. Genome Research. 17: 413-421.

Kohn, M. H., Murphy, W. J., Ostrander, E. A., and R. K. Wayne. 2006. Conservation genetics and the genomics toolbox. Trends in Ecology and Evolution. 21: 629-637.

Murphy, W. J., Pearks Wilkerson, A. J., Raudsepp, T., Agarwala, R., Schäffer, A. A., Stanyon, R., and B. P. Chowdhary. 2006. Novel gene acquisition on carnivore Y chromosomes. PLoS Genetics 2: e43.

Johnson, W. E., Eizirik, E., Pecon-Slattery, J., Murphy, W. J., Antunes, A., Teeling, E. C., and S. J. O'Brien. 2006. The late Miocene radiation of modern Felidae: a genetic assessment. Science 311: 73-77.

Murphy, W. J., Larkin, D., Everts van-der Wind, A., Bourque, G., Tesler, G., Auvil, L., Beever, J. E., Chowdhary, B. P., Galibert, F., Gatzke, L., Hitte, C., Meyers, S. N., Ostrander, E. A., Pape, G., Parker, H. G., Raudsepp, T., Rogatcheva, M. B., Schook, L. B., Skow, L. C., Welge, M., Womack, J. E., O'Brien, S. J., Pevzner, P. A., H. A. Lewin. 2005. Dynamics of mammalian chromosome evolution inferred from multispecies comparative maps. Science 309: 613-617.

Teeling, E. C., Springer, M. S., Madsen, O., Bates, P., O'Brien, S. J., and W. J. Murphy. 2005. A molecular phylogeny for bats illuminates biogeography and the fossil record. Science 307: 580-584.

Murphy, W. J., Pevzner, P. and S. J. O'Brien.  2004. Mammalian phylogenomics comes of age. Trends in Genetics 20: 631-639.

Roca, A. L., Kahila Bar-Gal, G., Eizirik, E., Helgen, K.M., Maria, R., Springer, M.S., O'Brien, S. J., and W. J. Murphy. 2004. Mesozoic origin for West Indian insectivores. Nature 429: 649-651.

Springer, M. S., Murphy, W. J., Eizirik, E., and S. J. O'Brien. 2003. Placental mammal diversification and the Cretaceous-Tertiary boundary. Proceedings of the National Academy of Sciences 100: 1056-1061.

Murphy, W. J., Eizirik, E., O'Brien, S. J., Madsen, O., Scally, M., Douady, C., Teeling, E. C., Ryder, O. A., Stanhope, M., De Jong, W. W. and M. S. Springer.  2001.  Resolution of the early placental mammal radiation using Bayesian phylogenetics.  Science  294: 2348-2351.

Murphy, W. J., Eizirik, E., Johnson, W. J., Zhang, Y. P., Ryder, O. A., and S. J. O'Brien.  2001.  Molecular phylogenetics and the origins of placental mammals.  Nature  409: 614-618.